r/interestingasfuck 4h ago

*Zebrafish embryo a 16-hour timelapse of an embryo forming its spinal cord.

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15.4k Upvotes

288 comments sorted by

u/Rip_Purr 4h ago

u/Tacosaurusman 4h ago

Thank you! So it is actually is a growing embryo. From your link:

"The video shows the development of a zebrafish embryo over a period of 16 hours. In discussion with Technology Networks, Liz and Henry go into more detail on exactly what we are seeing in the footage: "The embryo being imaged is a genetically modified organism expressing green fluorescent protein in a population of its sensory neurons. During the beginning of the movie, the main focus is on two rows of neurons in the spinal cord of the embryo (we are looking at its back and side). The cell bodies of these neurons extend two axons each in the spinal cord, forming a network to talk to the brain. They then send out a third axon, called a peripheral axon, which exits the spinal cord and innervates the skin of the embryo so it can sense touch. These axons grow incredibly long distances and establish complex, beautiful architectures." By the end of the video, the tip of the embryo's tail can be seen growing back into the movie's focal plane."

u/SquarePegRoundWorld 2h ago

expressing green fluorescent protein in a population of its sensory neurons

Future "ravers" are gonna be wild looking.

u/RealmKnight 1h ago

Cyberpunk biohackers with homebrew genetic engineered bioluminescent Chromatophores gonna be killing it on the dancefloor.

u/Almost_human-ish 4h ago

Thank you, you and your post are appreciated.

Still fucking cool though.

u/aquamarie8 3h ago

Thank you. I was trying to figure out how this was remotely human.

u/Guaymaster 3h ago

Zebrafish are the model organism to study vertebrate embryos, which is good enough: mammals are more complex, as part of it forms the placenta, but because of that it's not easy to see in real time.

u/JonnySoegen 1h ago

Also, I don't know if it's ethical to turn a human baby into a glowstick.

u/Guaymaster 1h ago

Only if you're caught

u/INRNME 59m ago

SCIENCE BITCH!

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u/Der_Redakteur 2h ago

Zebrafish? I thought that fish would look like seahorse but with stripes.

u/moneymakerbs 2h ago

Omg 😳thank you. I was watching this damn thing like, f** we found a way to watch a human baby’s spinal cord?!!!! 🤣🤣

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u/OneBudTwoBud 4h ago

I did that once

u/radioactive_sharpei 4h ago

I know many who didn't.

u/t-o-m-u-s-a 4h ago

Do you still keep in contact?

u/TheTerribleInvestor 4h ago

They're stuck to a piece of paper towel

u/Top-Construction-535 4h ago

Stuck inside a sock.

u/sirbolo 3h ago

Do you keep in contact with your congressmen?

u/t-o-m-u-s-a 1h ago

Only when they fuck me

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u/EnvironmentalCan381 2h ago

No!! they are in congress now.

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u/Chiliatch 4h ago

Unfortunately theyre all on government jobs now.

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u/lucylastic89 3h ago

spineless bastards

u/Connor-the-beast 3h ago

Yeah their trump supporters lol

u/IsNotPolitburo 2h ago

Whose Trump supporters?

u/ErraticDragon 2h ago

*There Trump supporters.

u/IsNotPolitburo 1h ago

Where Trump supporters?

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u/i_eat_da_poops 4h ago

I was the fastest swimmer in my division

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u/Snoo-85491 4h ago

Piece of cake.

u/Lonely-Swimming4564 3h ago

Zero effort too

u/sylanar 3h ago

Yeah,so what? I did it in 15 hours

u/TheTeflonDude 3h ago

Spine or it didnt happen

u/1h8fulkat 1h ago

So easy, I don't even remember it

u/Effurlife12 1h ago

Source?

u/FesteringNeonDistrac 3h ago

All I could think was here comes a lifetime of back problems.

u/Pu-Chi-Mao 3h ago

You're not a seahorse....

u/x_xiv 2h ago

you're a marvelous

u/sneakycatattack 1h ago

I did it twice! But my twins were not meant to be 🥲 

u/I_AM_FERROUS_MAN 1h ago edited 49m ago

This is the part my body didn't quite finish correctly.

Remember to take Folic Acid Vitamin B9 supplements newly pregnant Moms!!! It helps the nervous system form correctly!

Mayo Clinic, Cleveland Clinic, Johns Hopkins, NHS, CDC

u/Sure-Blueberry-5151 4h ago

u/CykoX90 4h ago

My thought exactly

u/Dinofours 4h ago

Mine too.

u/lonely_bohner1 4h ago

WE GOTTA STOP IT FROM TOUCHING EREN

u/Anvil_Prime_52 4h ago

Isayama just could not stop cooking could he

u/oxkwirhf 28m ago

Zebrafish for dinner tonight WE'RE EATING GOOD

u/DJ2SO 3h ago

Attack on Titan 🔥

u/Avocados_number73 3h ago

I thought it was the elden beast.

u/TheNorseFrog 2h ago

Both based on same mythical creature Hallucigenia. I think

u/Informal_Ad3244 2h ago

Not mythical. It’s a panarthropod from 500 million years ago.

u/Dart4jb1nks 3h ago

I thought of raava at first.

u/lonely_bohner1 3h ago

I thought of Reina first

u/DenjiTargaryen-PE 3h ago

I love my Attack on Titan peoples!

u/AssistanceSuch1230 3h ago

There it is

u/Quaesemaik 41m ago

That's crazy

u/doxtorwhom 1h ago

To you in 2,000 years

u/MartinchoLM 2h ago

Only came here looking for this comment, happy I found it.

u/KetoReeves 2h ago

Went straight to the comments.

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u/sublimeprince32 4h ago

Source? More?

u/schimshon 4h ago

Found the source here

u/sublimeprince32 3h ago

SWEET - thank you internet champion!!!

u/pinkpnts 1h ago

Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development - PMC https://share.google/FAswGRkHLLaDUkaoc

Here's the paper and not another video.

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u/CauliflowerIcy3283 2h ago

I thought 100% this was going to be a risk roll. thank you

u/doyouwantsomecocoa 4h ago

Is this real?

u/schimshon 4h ago

I think it's real. Looks like zebra fish development to me.

Edit: found the video link

u/sylanar 3h ago

Zebras don't live in the sea, you're probably thinking of sharks, a common misconception

u/piltonpfizerwallace 3h ago

Yeah looks like tiger shark development to me.

u/Veggies-are-okay 4h ago

Probably best in this day and age to assume fake unless an article is linked alongside it.

u/pinkpnts 2h ago edited 1h ago

It's real. I can't find the article for this video but my lab has these same modified zebrafish. It's used to study development.

Edit-found the paper: Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development - PMC https://share.google/FAswGRkHLLaDUkaoc

An Ath5:gap-GFP37 transgenic zebrafish embryo was used for imaging. This transgene labels different neurons in the retina (mainly ganglion cells and photoreceptor precursors).

u/inspanishthetable 2h ago

A real zebra fish

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u/5h15u1 4h ago

Elden beast

u/Oxyg3n-Potassium 4h ago

My first thought lol

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u/PaleBlueCod 4h ago

Everyone starts as a dick pic.

u/Agitated_Dish_6990 4h ago

Where's the long version?

u/Mythril_Zombie 3h ago

That's what she said.

u/Iamasadlittlething 4h ago

u/Tight_Fee_3853 2h ago

This is the comment I was looking for!

u/Monkeyboy999 4h ago

OP - Can you link a source please?

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u/Neeklow 4h ago edited 4h ago

Since many people have the doubt: yes it's real and that's very likely a zebrafish embryo here's an old Nikon post on YouTube of it

u/SarcasmisEasier 3h ago

The nerves on this guy. Can you believe it?

u/DogeAteMyHomework 4h ago

I came here for a 16-hour time-lapse to give 2026 a little hiatus. 

u/Biggest-bozo1234 4h ago

Bro finally grew a backbone, no more googoo gaga mentality

u/nachobel 3h ago

Someone should send this to Congress.

u/CartographerOk7579 3h ago

Hits harder when you’re a parent.

u/inspanishthetable 2h ago

of a zebra fish.

u/metabolitesafter9pm 4h ago

Now that is wild

u/Any_Classic_1667 4h ago

Gonna put this on my resume

u/Nadran_Erbam 4h ago

I can’t find the source, everyone copy paste the video with basically the same explanation.

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u/TyrantJaeger 4h ago

bro 3D printing himself

u/Quiverjones 3h ago

Looks nervous

u/it777777 3h ago

The miracle of life in a mostly lifeless universe

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u/Lucky_Veruca 3h ago

Big deal. I did that when I was a baby.

u/Federal_Routine_3109 3h ago

This is why I'm in med school wow my lord this is so insanely cool and amazing

u/man_juicer 3h ago

When somebody tells me to grow a spine:

u/Hot_Aspect7353 3h ago

As someone who watches the mandelbrot sequence to sleep this is incredibly calming.

u/HasGreatVocabulary 2h ago

so beautiful

u/Odd-Craft-9798 2h ago

So this is where it all went wrong

u/Beastw1ck 2h ago

TOOL music starts playing…

u/AlexiusPantalaimonII 2h ago

That is so beautiful

u/MoreThenAverage 2h ago

I need a banana next to it

u/What_a_fat_one 1h ago

See? It's a PERSON this early!!

Oh that's a zebrafish?

Ah! Well, nevertheless,

u/Canelosaurio 1h ago

This music overlay is trash. Should have played Battle Of Evermore by Led Zeppelin.

u/Bulletmaniac89 1h ago

And people say magic doesn't exist.

u/Gluedbymucus 4h ago

Life, uh, finds a way…

u/countcraig 1h ago

God is good

u/bumtrinket 4h ago

Wow. Is this a human embryo? It's like watching magic.

u/schimshon 4h ago

No, it's zebra fish (danio rerio)

u/Acceptable-Major-575 4h ago

like 3d printer

u/BigBibs 4h ago

Looks like roots

u/Tophigale220 4h ago

Man this is fascinating if it’s real

u/Grouchy-Engine1584 4h ago

This week on Mega Construction Projects! The Information Superhighway like you’ve never seen it before! It really is the “backbone” of our civilization.

u/pleth0ra 4h ago

Elden Beast

u/snappla 4h ago

This is SO fucking cool! 😮

u/Majestic-Routine2228 4h ago

We were the aliens all along

u/Just1n_Kees 4h ago

Where’s the rest of the 16hours?

u/Dart4jb1nks 4h ago

I thought it said 16 years at first and was like wtf…. Lol

u/GODLAND 3h ago

How did you get in there?

u/netuniya 3h ago

Wow! We all did that!

u/AapChutiyaHai 3h ago

That is freaking awesome.

u/paris_rogue 3h ago

I think death will be another adventure

u/Brizzle351 3h ago

Incredible!!! ❤️

u/tankpuss 3h ago

An embryo of what?

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u/FartsonmyFarts 3h ago

Its 23 seconds not 16 hours.

u/AStrayGod 3h ago

Spine? Completed it mate

u/needaburn 3h ago

Elden beast

u/Raelah 3h ago

Damn. It only takes 16 hours to form a spinal cord?

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u/PreposterousPringle 3h ago

And it already has more of a spine than Chuck Schumer.

u/JerkOffToBoobs 3h ago

That's only 16 hours? What's the length scale? What's the cell replication rate there? How is it possible to do that so fast?

u/pinkpnts 2h ago edited 1h ago

Zebrafish. 3 days post fertilization they're considered full fish. Able to feed on their own and absorb the yolk sac entirely at 7 days.

u/J0s3l1t0 3h ago

This is how the Rumbling began.

u/pseudoboi_band 3h ago

Send this to your Congress person, they probably need tips.

u/KenUsimi 2h ago

I remember visiting Florence once; the Natural History Museum there is amazing, they have these wax sculptures of humans. All the way down to the nervous system, so perfectly recreated that medical students study off them.

They were created hundreds of years ago, when studying human anatomy with cadavers was extremely controversial. They were created as a substitute. One consecrated dissection with master sculptors in attendance to recreate what they saw.

Well, almost; they also included the development of a human embryo in the womb. Except the female cadaver wasn’t pregnant, and they only had the one as a reference, so they just sorta… made it up. The embryo started as a tiny human, full formed, like a baby in a King’s Cake. It then grew in proportion to become baby sized.

Once again, master sculptors; this was all done to the highest standard, perfectly sculpted recreation of how the leading science of the day believed pregnancy proceeded. Hey, not like they could peek inside!

Now we can watch a spinal column build itself in near-real time. We’ve come so far. Let’s keep that up.

u/Darwincroc 2h ago

That’s wild!

u/TacticaLuck 2h ago

Alright everybody now let's get out there and make some friends! There are no mistakes even if you befriend yourself

u/Aliencoy77 2h ago

Does it use the electromagnetic spectrum to determine its spread?

u/Negotiation-Narrow 2h ago

That was not 16 hours. 

u/PixelCrunchX 2h ago

Awww, on his way to getting chronic back pain already ❤️

u/KenseiHimura 2h ago

Cool, but knowing that's a nervous system for some reason makes me think it'd feel painful. You know, if there was enough of a brain to process pain.

u/diodenkn 2h ago

I feel like humanity was never meant to see this

u/Gotrek6 2h ago

Eren did it faster and with more conviction

u/hendrix320 2h ago

So the ass is where life starts. Good to know

u/SteroidSandwich 2h ago

At least someone has a spine

u/GroovinChip 2h ago

Forbidden Mario Kart track development

u/thoroughbred901 2h ago

AOT vibes

u/WoodooTheWeeb 2h ago

Maris, Fathom of the night

u/Spyrothedragon9972 2h ago

Incredible

u/SkooksOnReddit 2h ago

Real shit?

u/Karnij13 2h ago

Eren?

u/HalfOffSnoke 1h ago

That's wild. Thanks for sharing

u/Zealousideal-Ad7707 1h ago

Processing img ljonxstr1tdg1...

u/Splodeybeholdja 1h ago

Now if only Congress could do this. 

u/Uk_KingsStar 1h ago

That’s the fucker that got Ymir

u/Striking-Performer66 1h ago

I thought my time-lapse video of a pot plant was cool. This almost made me cry as I smiled in amazement. That's literally a life being formed 🥲

u/ExplodingSteve 1h ago

Yall know this is a bot right?

u/Plane-Koala3478 1h ago

Wow science is incredible

u/Pale_Performance_510 1h ago

Processing img tbmdsaxz2tdg1...

Reddit really wants me to see this post

u/blarg_somthing 1h ago

Is the bottom the brain?

u/flibbell 1h ago

Visions of AoT

u/MulfordnSons 1h ago

This might be the coolest thing I have ever seen

u/Fisher2087 1h ago

Where my back problems started.

u/Librarian-Rare 1h ago

The video wasn’t 16 hours..? Not enough close. Some people are so stupid.

Cool video though 😎

u/armaghetto 1h ago

“And that kids, is where Titans come from”

u/Ya-Dikobraz 58m ago

On a tangent, internationally it is only allowed to develop a human embryo for 14 days (for experimental/ research purposes). Although some people want to extend that limit to 28 days now.

P.S. I realise the embryo in OP's post isn't human.

u/Rath_Brained 56m ago

So you are telling me that I have been dealing with backpack for so long, when I could just rip mine out and grow a new, better one in 16 hours?!

I have been bamboozled my whole life! /jk

u/alienwalk 48m ago

That was only 24 seconds, not 16 hours.

u/BobSacamano47 47m ago

Is there some way I could redo mine?

u/sarcastic_wanderer 39m ago

THE NEURAL TUUUUUUBE

u/Affectionate_Use406 32m ago

it’s a dolphin

u/SeveralAnteater292 23m ago

If you really think about it, biology is absolutely bonkers

u/ihadtoresignupdarn 7m ago

Kinda crazy that we form from nothing into humans

u/Renojackson32 0m ago

I wanna see the rest